Allison Spence grew up in the southern suburbs of Illinois. Allison served as a three year varsity starter at Marist high school where she was a three year all-conference nominee, three time all area selection, and 2014 MVP. Allison then went on to graduate from Illinois State University in 2019 where she played first base and served as the captain of her team during her junior and senior seasons. At ISU, Spence assisted her team in winning a conference championship and holds ISU and MVC records. She was three-time All-Conference, was on the NFCA All-Mideast Region team, and held a career batting average of .321.